Lanzhou Institute of Chemistry has made progress in the development of new biomaterials based on graphene

Preparation of Hydrogels (a) and Photographs of Rat Wound Healing Experiments (b)

The Polymer Tribology Group of the State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, has made progress in the research and application of new biomaterials based on graphene.

Graphene has outstanding mechanical properties and biocompatibility, and its use as a reinforcing filler can significantly improve the mechanical properties of biomaterials. Based on this, the researchers carried out a series of preparations based on graphene composite biomaterials and their research work in biomedical applications, and achieved good research progress.

(1) Hydroxyapatite nanorods/graphene composites and casein phosphopeptides/graphene composites were prepared by using graphene as the bone reinforcement material. The results confirmed that the introduction of graphene can significantly improve the mechanical properties of the material and bone. The ability to integrate, and can promote osteoblast adhesion and growth, the composite material exhibits excellent biocompatibility and biological activity. Some of the findings were published in the magazines Carbon (2014, 66, 407-416) and J. Phys. Chem. C (2013, 117, 10375–10382).

(2) A graphene/silver/polymer (polyacrylic acid and polymethylene bisacrylamide) composite hydrogel artificial dressing was prepared. The preparation process is shown in Figure a. The dressing exhibited excellent antibacterial properties and wound repair ability, and it was used to treat artificial wounds in rats. The wound healing rate after 15 days can reach 98% (Fig. b).

The study provided new wound healing materials for clinical applications and also provided new ideas and methods for the development of new wound healing materials. The results of the relevant research will soon be published in Adv. Funct. Mater. (DOI: 10.1002/adfm.201304202).

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