Product Description
Raw 98% purity Quinine powder effect on Antimalarial
Product name: Quinine
Alias: Chinin; Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-; Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)-; Kinin; Quinina;
CAS Number: 130-95-0
EINECS number: 205-003-2
Molecular Formula: C20H24N2O2
Molecular weight: 322.41700
Appearance and properties: Orthorhombic needles, odorless
Density: 1.21g/cm3
Melting point: 176-177oC
Boiling point: 495.9oC at 760mmHg
Flash point: 253.7oC
Refractive index: 1.625 (15oC)
Stability: Stable under normal temperatures and pressures. May discolor on exposure to light.
Storage conditions: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store below 40oC.
Steam pressure: 0mmHg at 25°C
Packing level: III
Hazard Category: 6.1(b)
Customs Code: 29392110
Dangerous goods transport code: UN 1544
WGK Germany: 3
Hazard category code: R22; R36/37/38
Safety instructions: S26-S37/39
Dangerous goods mark: Xn
Â
Quinine is a quinoline derivative and has a strong killing effect on various erythrocytic schizonts of Plasmodium. It can combine with Plasmodium DNA to form complexes, inhibit DNA replication and RNA transcription, thereby inhibiting the protein synthesis of protozoa, but the effect is weaker than chloroquine. It can also reduce the oxygen consumption of Plasmodium, inhibit the phosphorylase in Plasmodium and interfere with its sugar metabolism. It also causes agglutination of malarial pigments, but it develops slowly and rarely forms large clumps. In the blood, a certain concentration of Quinine can lead to premature rupture of the parasitized red blood cells, thus preventing the schizont from maturing. Quinine has no effect on the infrared phase and does not cure benign malaria. A long course of treatment can cure P. falciparum, but it has no direct effect on the gametophyte of P. falciparum, so it cannot interrupt transmission. In addition, Quinine has an inhibitory effect on the myocardium, prolongs the refractory period, slows conduction, and weakens its contractility. There is a weak excitatory effect on the uterus during pregnancy.
Quinine COA:Â
Product name |
Quinine | |||
CAS No. |
130-95-0 |
Outer Packing |
1KG/bag |
|
Production date |
2017.02.17 |
Shelf life |
2022.02.16 | |
Standard adopted |
Enterprise Standard | |||
Items of analysis |
Specification |
Results |
||
Character |
product is a white amorphous or crystalline powder |
White crystalline powder |
||
Specific rotation |
About -160° (ethanol) |
-162° |
||
Melting point |
175ºC~178ºC |
175ºC |
||
Heavy metals |
≤20ppm |
<20ppm |
||
Dry weight loss |
≤1.0% |
0.6% |
||
Other cinchona alkaloids |
Must comply with the requirements |
Complies | ||
Assay |
C20H24N2O2 ≥98% |
99.2% |
||
Conclusion |
Qualified |
Effect
Quinine is an important antimalarial drug for the erythrocytic protozoa of P. falciparum that inhibits its reproduction or kills it. Quinine also inhibits myocardial contractility and increases uterine rhythmic contraction.
Taboo
Pregnant women are disabled, quinine has oxytocin, can pass the placenta, causing fetal hearing damage and congenital defects of the central nervous system, limbs. Nursing women with caution.
For patients with asthma, atrial fibrillation and other severe heart diseases, glucose-6-phosphate dehydrogenase deficiency, myasthenia gravis, and optic neuritis should be used with caution.
Cardiomyopathy and pregnant women are disabled. Treatment of cerebral malaria with quinine is dangerous, and it is dangerous for people who are allergic to quinine.
Packaging: foil bag or tin.
Payment: Bank Transfer, Western Union, Money GramÂ
Express: EMS, DHL, FedEx, etc(door-to-door)Â
Delivery: Safe & timely, around 1-3 days after paymentÂ
Â
Quick Detail:
- Delivery: Parcels would be arranged within 12 hours upon receipt your payment.
- Packing: Steroids powders would be packed discreetly enough to cross customsÂ
worldwide safely. Packing like traditional chinese food, washing and bathing items and otherÂ
equipments, etc...
- Extra service: Photos of of package would be provided for you to tell apart the steroids.Â
Tracking number would be offered once it is released.Â
- After-sale service: Any questions after you got the parcel, please contact us for the first time. Problems would be solved for you immediately.
Â
We also supply Pre-mixed, Sterile and Painless liquid. If any interested, pls kindly contact me. I'm Amy.Â
This is how a order arranged here :
Parcel would be arranged with 12 hours upon receipt of your payment .
Usually, the picture of package and the tracking number will be offeredÂ
next day.
Photos would be offered to tell apart the products . (send togetherÂ
steroids with real and original products )
Tracking number Send by EMS, the tracking number is availabe within 12Â
hours . The info would be trackable that day or 1 day later.Â
Product Description
Raw 98% purity Quinine powder effect on Antimalarial
Product name: Quinine
Alias: Chinin; Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-; Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)-; Kinin; Quinina;
CAS Number: 130-95-0
EINECS number: 205-003-2
Molecular Formula: C20H24N2O2
Molecular weight: 322.41700
Appearance and properties: Orthorhombic needles, odorless
Density: 1.21g/cm3
Melting point: 176-177oC
Boiling point: 495.9oC at 760mmHg
Flash point: 253.7oC
Refractive index: 1.625 (15oC)
Stability: Stable under normal temperatures and pressures. May discolor on exposure to light.
Storage conditions: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store below 40oC.
Steam pressure: 0mmHg at 25°C
Packing level: III
Hazard Category: 6.1(b)
Customs Code: 29392110
Dangerous goods transport code: UN 1544
WGK Germany: 3
Hazard category code: R22; R36/37/38
Safety instructions: S26-S37/39
Dangerous goods mark: Xn
Â
Quinine is a quinoline derivative and has a strong killing effect on various erythrocytic schizonts of Plasmodium. It can combine with Plasmodium DNA to form complexes, inhibit DNA replication and RNA transcription, thereby inhibiting the protein synthesis of protozoa, but the effect is weaker than chloroquine. It can also reduce the oxygen consumption of Plasmodium, inhibit the phosphorylase in Plasmodium and interfere with its sugar metabolism. It also causes agglutination of malarial pigments, but it develops slowly and rarely forms large clumps. In the blood, a certain concentration of Quinine can lead to premature rupture of the parasitized red blood cells, thus preventing the schizont from maturing. Quinine has no effect on the infrared phase and does not cure benign malaria. A long course of treatment can cure P. falciparum, but it has no direct effect on the gametophyte of P. falciparum, so it cannot interrupt transmission. In addition, Quinine has an inhibitory effect on the myocardium, prolongs the refractory period, slows conduction, and weakens its contractility. There is a weak excitatory effect on the uterus during pregnancy.
Quinine COA:Â
Product name |
Quinine | |||
CAS No. |
130-95-0 |
Outer Packing |
1KG/bag |
|
Production date |
2017.02.17 |
Shelf life |
2022.02.16 | |
Standard adopted |
Enterprise Standard | |||
Items of analysis |
Specification |
Results |
||
Character |
product is a white amorphous or crystalline powder |
White crystalline powder |
||
Specific rotation |
About -160° (ethanol) |
-162° |
||
Melting point |
175ºC~178ºC |
175ºC |
||
Heavy metals |
≤20ppm |
<20ppm |
||
Dry weight loss |
≤1.0% |
0.6% |
||
Other cinchona alkaloids |
Must comply with the requirements |
Complies | ||
Assay |
C20H24N2O2 ≥98% |
99.2% |
||
Conclusion |
Qualified |
Effect
Quinine is an important antimalarial drug for the erythrocytic protozoa of P. falciparum that inhibits its reproduction or kills it. Quinine also inhibits myocardial contractility and increases uterine rhythmic contraction.
Taboo
Pregnant women are disabled, quinine has oxytocin, can pass the placenta, causing fetal hearing damage and congenital defects of the central nervous system, limbs. Nursing women with caution.
For patients with asthma, atrial fibrillation and other severe heart diseases, glucose-6-phosphate dehydrogenase deficiency, myasthenia gravis, and optic neuritis should be used with caution.
Cardiomyopathy and pregnant women are disabled. Treatment of cerebral malaria with quinine is dangerous, and it is dangerous for people who are allergic to quinine.
Packaging: foil bag or tin.
Payment: Bank Transfer, Western Union, Money GramÂ
Express: EMS, DHL, FedEx, etc(door-to-door)Â
Delivery: Safe & timely, around 1-3 days after paymentÂ
Â
Quick Detail:
- Delivery: Parcels would be arranged within 12 hours upon receipt your payment.
- Packing: Steroids powders would be packed discreetly enough to cross customsÂ
worldwide safely. Packing like traditional chinese food, washing and bathing items and otherÂ
equipments, etc...
- Extra service: Photos of of package would be provided for you to tell apart the steroids.Â
Tracking number would be offered once it is released.Â
- After-sale service: Any questions after you got the parcel, please contact us for the first time. Problems would be solved for you immediately.
Â
We also supply Pre-mixed, Sterile and Painless liquid. If any interested, pls kindly contact me. I'm Amy.Â
This is how a order arranged here :
Parcel would be arranged with 12 hours upon receipt of your payment .
Usually, the picture of package and the tracking number will be offeredÂ
next day.
Photos would be offered to tell apart the products . (send togetherÂ
steroids with real and original products )
Tracking number Send by EMS, the tracking number is availabe within 12Â
hours . The info would be trackable that day or 1 day later.Â
Various raw materials are used during the production process of water reducer. High-quality raw materials are indispensable for good products. East Chem is mainly engaged in the operation of water-reducing agents, supplemented by various raw materials, to create a more comfortable and efficient platform for customers, and to provide you with one-stop procurement services.
Raw Materials of Water Reducer
Raw Materials Of Water Reducing Agent,Meta Acrylic Acid,Poly Propenoic Acid,Dimethyl Acrylic Acid
Shenyang East Chemical Science-Tech Co., Ltd. , https://www.eastchemy.com